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Medical Xpress - medical research advances and health news

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Mutations in two gene pairs point to a promising drug target in 5% of adult cancers

Medical Xpress - medical research advances and health news
Summary
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88% Informative

About 5% of adult cancers rely heavily on a gene called PELO to survive and that disabling the gene kills those cancer cells.

The finding, described in Nature , is a new synthetic lethality—a pair of genetic changes that together kill cancer cells together.

Genetic testing could identify cancer patients with FOCAD or TCC37 mutations who would benefit from new drugs.

VR Score

93

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96

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50

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formal

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English

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54

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long-living

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