GLP-1 Agonists Reduce Fat Mass
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fat mass lossScienceDaily
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Health
Genetic evidence that diabetes drug GLP-1 receptor agonists achieve weight loss primarily by reducing fat mass more than muscle
80% Informative
Glucagon -like peptide-1 ( GLP-1 ) receptor agonists, a class of medications widely used in the treatment of type 2 diabetes (T2D), have shown significant effectiveness in both lowering blood sugar levels and aiding weight loss due to their unique pharmacological mechanisms.
A research team from the University of Hong Kong assessed the impact of GLp-1 receptor agonist in weight loss through genetic studies, aiming to understand whether the use of these medications reduces weight due to muscle or fat mass loss.
The research team found that participants with.
genetic makeup mimicking the effect of GLP .
agonists leads to reductions in both lean mass (whole-body fat-.
The study was led by Professor Ryan Au Yeung Shiu-lun , Assistant Professor in the School of Public Health , HKUMed.
Liang Yiwen , a PhD student in the same School was the first author of the study.
Other research team members included Professor Eric Wan Yuk-fai and Dr Luo Shan from the Department of Family Medicine and Primary Care .
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