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CRISPR-Cascade test detects bloodstream infections in minutes without amplification

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Summary
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93% Informative

CRISPR-Cascade assay achieves attomolar sensitivity and incorporates an OR-gated logic function to identify multiple pathogens simultaneously through DNA from pathogens associated with bloodstream infections.

In testing, the assay successfully identified Methicillin-Sensitive Staphylococcus aureus ( MSSA ), MRSA , Escherichia coli (E. coli), and Hepatitis B Virus in pathogen DNA-spiked blood samples within ten minutes .

VR Score

96

Informative language

98

Neutral language

74

Article tone

formal

Language

English

Language complexity

89

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not offensive

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not hateful

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not detected

Time-value

long-living

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